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Form	MW
(R)-Doxazosin This page	451.48
(S)-Doxazosin	451.48

(R)-Doxazosin

a1-adrenoceptor Agonist

(R)-Doxazosin is an isomer of Doxazosin that acts as a selective and orally active alpha-1 adrenoceptor agonist. This compound exhibits significant antihypertensive and ocular hypotensive activities by preferentially targeting postsynaptic alpha-1 receptors, leading to a reduction in total peripheral resistance without compromising cardiac output. (R)-Doxazosin is valuable in research applications focused on cardiovascular regulation and disorders involving blood pressure modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	70918-17-1
Applications	a1-adrenoceptor Agonist
Formula	C₂₃H₂₅N₅O₅
Molecular Weight	451.48
Synonyms	(R)-UK 33274
SMILES	O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)[C@@H]4OC5=CC=CC=C5OC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.