Fig. 1 · Structure
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(R)-DZD1516
R Enantiomer of DZD1516
(R)-DZD1516 is the R enantiomer of DZD1516, serving as a potent and selective inhibitor of the HER2 receptor. This compound demonstrates significant inhibition of HER2 signaling pathways, which are often implicated in the progression of various cancers. (R)-DZD1516 is valuable for research applications focused on cancer biology, particularly in studies evaluating therapeutic strategies targeting HER2-positive tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2387570-03-6 |
| Applications | R Enantiomer of DZD1516 |
| Formula | C28H27F2N7O3 |
| Molecular Weight | 547.56 |
| SMILES | COC1=CC2=C(C(NC3=CC=C(C(C)=C3)OC4=CC5=NC=NN5C=C4)=NC=N2)C(O[C@@H]6CCN(CC6(F)F)C)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.