Fig. 1 · Structure
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(R)-Fasiglifam
Isomer
(R)-Fasiglifam is the isomer of Fasiglifam, serving as an important experimental control in research. Fasiglifam is a selective and potent agonist of the G protein-coupled receptor GPR40, exhibiting an EC50 of 72 nM. This compound is primarily utilized in studies related to glucose metabolism and insulin secretion, highlighting its relevance in investigating metabolic disorders such as type 2 diabetes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1234474-57-7 |
| Applications | Isomer |
| Formula | C29H32O7S |
| Molecular Weight | 524.63 |
| Synonyms | (R)-TAK-875 |
| SMILES | CC1=C(C(C)=CC(OCCCS(C)(=O)=O)=C1)C2=CC(COC3=CC=C([C@H](CO4)CC(O)=O)C4=C3)=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.