Fig. 1 · Structure

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(R)-JNJ-40418677

R-Enantiomer of JNJ-40418677

(R)-JNJ-40418677 is the R-enantiomer of the compound JNJ-40418677, which functions primarily as a selective modulator of the mGlu2 receptor. This compound exhibits promising biological activity by potentially enhancing cognitive functions and mitigating anxiety-related behaviors. Research applications include studies on neuropharmacology and the investigation of therapeutic targets for neurological disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1146594-85-5
Applications R-Enantiomer of JNJ-40418677
Formula C26H22F6O2
Molecular Weight 480.44
SMILES
CC(C)C[C@H](C1=CC(C2=CC=C(C=C2)C(F)(F)F)=CC(C3=CC=C(C=C3)C(F)(F)F)=C1)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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