Fig. 1 · Structure
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(R)-L 888607
Isomer
(R)-L 888607 is the isomer of L 888607, serving as a valuable experimental control. As a potent and selective agonist of the CRTH2 receptor, it demonstrates high affinity, with a Ki value of 4 nM. This compound has applications in studying various physiological events and metabolites, providing insights into immune response modulation and related pathways. Its oral bioavailability further facilitates in vivo research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2446042-90-4 |
| Applications | Isomer |
| Formula | C19H15ClFNO2S |
| Molecular Weight | 375.84 |
| SMILES | O=C(O)C[C@H]1CCN2C1=C(SC3=CC=C(Cl)C=C3)C4=C2C=C(F)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.