Fig. 1 · Structure
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(R)-Mirtazapine
5-HT3 Receptor Antagonist
(R)-Mirtazapine is a selective 5-HT3 receptor antagonist known for its antinociceptive properties demonstrated in animal models of acute thermal nociception. This R( )-enantiomer of Mirtazapine contributes to various neurological studies, particularly in the context of pain modulation and serotonin pathway interactions. (R)-Mirtazapine undergoes metabolism primarily by the enzyme CYP3A4, making it a relevant compound for pharmacokinetic studies in drug metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 61364-37-2 |
| Applications | 5-HT3 Receptor Antagonist |
| Formula | C17H19N3 |
| Molecular Weight | 265.35 |
| Synonyms | (R)-Org3770; (R)-6-Azamianserin |
| SMILES | CN1C[C@@]2([H])C3=CC=CC=C3CC4=CC=CN=C4N2CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.