Fig. 1 · Structure
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(R)-ML375
Cat. No.
B10859
CAS
1488362-56-6
ML375 Enantiomer
(R)-ML375 is an enantiomer of ML375, primarily targeting the muscarinic acetylcholine receptor subtype M5 (hM5). This compound is characterized by its lack of significant activity on M5 mAChR, exhibiting an IC50 greater than 30 μM. (R)-ML375 is suitable for studies exploring the role of muscarinic receptors in physiological and pathological processes, providing a valuable tool for chemical research in neuronal signaling and related fields.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1488362-56-6 |
| Applications | ML375 Enantiomer |
| Formula | C23H15ClF2N2O2 |
| Molecular Weight | 424.83 |
| Synonyms | (R)-VU0483253 |
| SMILES | O=C1N2[C@](N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C=C4)C5=C1C=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.