Fig. 1 · Structure
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(R)-ND-336
MMP-9 Inhibitor
(R)-ND-336 is a selective inhibitor of matrix metalloproteinase-9 (MMP-9), exhibiting a Ki value of 19 nM. It also demonstrates inhibitory activity against MMP-2 (Ki=127 nM) and MMP-14 (Ki=119 nM). This compound is useful for investigating therapeutic approaches in conditions such as diabetic foot ulcers (DFUs) and plays a critical role in studies related to tissue remodeling and wound healing.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2252493-33-5 |
| Applications | MMP-9 Inhibitor |
| Formula | C16H18ClNO3S2 |
| Molecular Weight | 371.90 |
| SMILES | NCC1=CC=C(OC2=CC=C(C=C2)S(C[C@@H]3SC3)(=O)=O)C=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.