Fig. 1 · Structure
Documents & Downloads
(R)-ONO-2952
ONO-2952 Enantiomer
(R)-ONO-2952 is a highly selective enantiomer of ONO-2952, acting as a potent antagonist of the translocator protein (TSPO) with inhibition constants (Kis) ranging from 0.33 to 9.30 nM for both rat and human TSPO. This compound exhibits a notable selectivity for TSPO over other receptors, transporters, ion channels, and enzymes. Its significant biological activity makes it a valuable tool for research applications focused on neuroinflammation, neuroprotection, and various TSPO-related pathways in cellular and molecular studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2988224-39-9 |
| Applications | ONO-2952 Enantiomer |
| Formula | C22H20ClFN2O2 |
| Molecular Weight | 398.86 |
| SMILES | CC(N1CC2(CC2)C3=C(NC4=CC=CC(F)=C43)[C@H]1C5=C(C=C(C=C5)Cl)OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.