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(R,R)-Abacavir

(R,R)-enantiomer of Abacavir

(R,R)-Abacavir is the (R,R)-enantiomer of the nucleoside reverse transcriptase inhibitor Abacavir. This compound exhibits potent antiviral activity by inhibiting HIV replication, making it valuable for research in virology and HIV/AIDS treatment. Additionally, (R,R)-Abacavir demonstrates anticancer properties in prostate cancer cell lines and can penetrate the blood-brain barrier, where it may also suppress telomerase activity, providing insights for studies in oncology and neurobiology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1443421-67-7
Applications	(R,R)-enantiomer of Abacavir
Formula	C₁₄H₁₈N₆O
Molecular Weight	286.33
SMILES	OC[C@@H](C=C1)C[C@H]1N2C3=NC(N)=NC(NC4CC4)=C3N=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.