Fig. 1 · Structure
Documents & Downloads
(R,R)-Reboxetine mesylate
Antidepressant Agent
(R,R)-Reboxetine mesylate acts as a selective noradrenaline reuptake inhibitor, targeting the norepinephrine system to provide antidepressant effects. This enantiomer exhibits improved bioavailability and low affinity for alpha-adrenergic and muscarinic receptors, contributing to its reduced toxicity profile in animal models. Its primary application lies in the research of mood disorders and the pharmacological assessment of antidepressant therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 105017-39-8 |
| Applications | Antidepressant Agent |
| Formula | C20H27NO6S |
| Molecular Weight | 409.50 |
| Synonyms | (R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate; (R,R)-(-)-Reboxetine mesylate |
| SMILES | CCOC1=CC=CC=C1O[C@@H]([C@@]2([H])CNCCO2)C3=CC=CC=C3.CS(=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.