Fig. 1 · Structure
Documents & Downloads
(R,S)-Ivosidenib
Enantiomer Of Ivosidenib
(R,S)-Ivosidenib is the racemic mixture of the enantiomer ivosidenib, which primarily targets mutant isocitrate dehydrogenase 1 (IDH1). Although it exhibits reduced biological activity compared to its active counterpart, it is utilized in research surrounding IDH1 mutant-associated cancers. This compound serves as a valuable tool for exploring the implications of IDH1 mutations in tumorigenesis and therapeutic responses.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2070009-31-1 |
| Applications | Enantiomer Of Ivosidenib |
| Formula | C28H22ClF3N6O3 |
| Molecular Weight | 582.96 |
| Synonyms | (R,S)-AG-120 |
| SMILES | FC1(F)CC(NC([C@H](N(C2=CC(F)=CN=C2)C([C@@H](N3C4=NC=CC(C#N)=C4)CCC3=O)=O)C5=CC=CC=C5Cl)=O)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.