Fig. 1 · Structure
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(R)-Safinamide
Safinamide (R)-Enantiomers
(R)-Safinamide, the (R)-enantiomer of safinamide, functions as a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting an IC50 value of 0.45 μM. This compound has significant implications in research focused on neurodegenerative disorders such as Parkinson's disease, where modulation of MAO-B activity is critical. Its ability to influence dopaminergic signaling pathways makes it a valuable tool for investigating therapeutic strategies in neurological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 174756-44-6 |
| Applications | Safinamide (R)-Enantiomers |
| Formula | C17H19FN2O2 |
| Molecular Weight | 302.34 |
| Synonyms | FCE 28073; (R)-EMD 1195686 |
| SMILES | FC1=CC=CC(COC2=CC=C(C=C2)CN[C@@H](C(N)=O)C)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.