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Form	MW
(R)-thioxo-Dxd This page	509.55
thioxo-Dxd	509.55

(R)-thioxo-Dxd

Camptothecin Derivative

(R)-thioxo-Dxd is a Camptothecin derivative that targets topoisomerase I, inhibiting DNA replication and inducing apoptosis in cancer cells. This compound can be conjugated to monoclonal antibodies using linkers to create antibody-drug conjugates (ADCs), facilitating targeted deliverance of cytotoxic agents. It is particularly useful for research focusing on tumors with elevated HER2 or TROP2 expression.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2806052-36-6
Applications	Camptothecin Derivative
Formula	C₂₆H₂₄FN₃O₅S
Molecular Weight	509.55
SMILES	OCC(N[C@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=S)=NC6=CC(F)=C(C)C(CC1)=C62)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.