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Form	MW
thioxo-Dxd This page	509.55
(R)-thioxo-Dxd	509.55

thioxo-Dxd

Anticancer Agent

Thioxo-Dxd is a derivative of Camptothecin that acts as an anticancer agent by targeting tumor cells. This compound can be conjugated to monoclonal antibodies through linkers, facilitating the creation of antibody-drug conjugates (ADCs) for targeted therapy. Thioxo-Dxd is particularly relevant for research focused on tumors characterized by elevated HER2 or TROP2 expression, enabling potential advancements in targeted cancer treatments.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2806052-35-5
Applications	Anticancer Agent
Formula	C₂₆H₂₄FN₃O₅S
Molecular Weight	509.55
SMILES	OCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=S)=NC6=CC(F)=C(C)C(CC1)=C62)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.