Fig. 1 · Structure
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(R)-Zunsemetinib
Isomer
(R)-Zunsemetinib is the isomer of Zunsemetinib, serving as an important experimental control in research studies. Zunsemetinib functions as a selective inhibitor of p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2), demonstrating potential therapeutic applications in immuno-inflammatory diseases. This compound is essential for elucidating MK2 pathway involvement in various biological processes and for validating experimental findings related to inflammation and immune response modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1640282-44-5 |
| Applications | Isomer |
| Formula | C25H22ClF2N5O3 |
| Molecular Weight | 513.92 |
| Synonyms | (R)-ATI-450; (R)-CDD-450 |
| SMILES | FC1=CC(F)=CN=C1COC2=C(Cl)C(N(C3=CC(C4=NC(C(C)(C)O)=NC=C4)=NC=C3C)C(C)=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.