Fig. 1 · Structure
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(Rac)-BAY-985
TBK1 Inhibitor
(Rac)-BAY-985 is a potent ATP-competitive inhibitor targeting TBK1, demonstrating a remarkable IC50 of 1.5 nM. This compound exhibits significant antitumor efficacy, making it a valuable tool for cancer research. Its selective inhibition of TBK1 provides insights into the role of this kinase in various biological processes and disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2101925-20-4 |
| Applications | TBK1 Inhibitor |
| Formula | C27H30F3N9O |
| Molecular Weight | 553.58 |
| SMILES | O=C(N1CCN(C(C2=CC(NC3=NC4=CC=C(C5=NC=NC(N(C)C)=C5)C=C4N3)=NC=C2)C)CC1)CC(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.