(Rac)-Bedaquiline-d6 is a deuterium-labeled analogue of Bedaquiline, a diarylquinoline compound that targets Mycobacterium tuberculosis (Mtb) by inhibiting F1FO-ATP synthase, specifically affecting the c- and ε-subunits. This agent also exhibits uncoupler activity which contributes to its mechanism of action. (Rac)-Bedaquiline-d6 is utilized in research focused on multi-drug resistant tuberculosis, offering insights into drug metabolism and efficacy of therapeutic strategies.
(Rac)-Bedaquiline-d6 is a deuterium-labeled analogue of Bedaquiline, a diarylquinoline compound that targets Mycobacterium tuberculosis (Mtb) by inhibiting F1FO-ATP synthase, specifically affecting the c- and ε-subunits. This agent also exhibits uncoupler activity which contributes to its mechanism of action. (Rac)-Bedaquiline-d6 is utilized in research focused on multi-drug resistant tuberculosis, offering insights into drug metabolism and efficacy of therapeutic strategies.
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