Fig. 1 · Structure
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(Rac)-BI 703704
sGC Activator
(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC). This compound has demonstrated the ability to mitigate renal damage progression in the ZSF1 rat model, suggesting its potential therapeutic application in diabetic nephropathy. The modulation of sGC activity may offer novel insights into the treatment of related renal disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1423067-48-4 |
| Applications | sGC Activator |
| Formula | C32H37N3O4S |
| Molecular Weight | 559.72 |
| SMILES | O=C(C1C2CN(C3=NC(C4=CC(C)=CC=C4OCC5=CC=C(C(N6CCCCC6)=O)C=C5C)=CS3)CC1CC2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.