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(Rac)-Luciferin 6′-methyl ether sodium

PpyLuc Inhibitor

(Rac)-Luciferin 6′-methyl ether sodium is a potent inhibitor of the firefly luciferase derived from Photinus pyralis (PpyLuc), exhibiting an IC50 of 0.1 μM. This analog of D-luciferin demonstrates non-specific interactions at both ATP- and luciferin-binding sites within the PpyLuc active site. It is utilized in research applications involving bioluminescence assays and studies on enzyme kinetics, providing insights into luciferase activity and inhibition.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	646450-23-9
Applications	PpyLuc Inhibitor
Formula	C₁₂H₉N₂NaO₃S₂
Molecular Weight	316.33
Synonyms	(Rac)-6′-Methoxyluciferin sodium
SMILES	O=C(C1N=C(C2=NC3=C(S2)C=C(OC)C=C3)SC1)O[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.