Fig. 1 · Structure
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Rafutrombopag diolamine
Thrombopoietin Receptor Agonist
Rafutrombopag diolamine is a potent thrombopoietin receptor agonist that enhances platelet production by stimulating megakaryocyte differentiation and proliferation. This compound is primarily utilized in research related to thrombocytopenia and other platelet-related disorders, offering insights into the mechanisms of thrombopoiesis and potential therapeutic strategies. Its biological activity supports studies focused on hematological responses and related signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1257792-42-9 |
| Applications | Thrombopoietin Receptor Agonist |
| Formula | C29H36N6O7 |
| Molecular Weight | 580.64 |
| SMILES | O=C1N(N=C(/C1=N/NC2=C(C(C3=CC=C(C(O)=O)O3)=CC=C2)O)C)C4=CC=C(CCCC5)C5=C4.NCCO.NCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.