Ranolazine dihydrochloride

Catalog No.: A10781

Ranolazine dihydrochloride

Ranolazine dihydrochloride Chemical Structure

CAS NO. 95635-56-6

Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP).

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500 mg
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Biological Activity

Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP).
In vitro DMSO 90 mg/mL (179.83 mM)
Water 90 mg/mL (179.83 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.98 mL 99.91 mL 199.82 mL
0.5 mM 4 mL 19.98 mL 39.96 mL
1 mM 2 mL 9.99 mL 19.98 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 500.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10781
CAS No. 95635-56-6
Formula C24H35Cl2N3O4
M. Wt 500.46
Purity >98%
Synonyms CVT 303 dihydrochloride, CVT-303, CVT303; RS 43285, RS43285, RS-43285
SMILES O=C(NC1=C(C)C=CC=C1C)CN2CCN(CC(O)COC3=CC=CC=C3OC)CC2.[H]Cl.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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