Rapirosiran

Catalog No.: A68985
Non-alcoholic steatohepatitis
Rapirosiran is an N-acetylgalactosamine-conjugated small interfering RNA that specifically targets mRNA of hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) in the liver. Inhibition of HSD17B13 via Rapirosiran is associated with a reduced risk of chronic liver disease. This reagent is valuable for investigating the mechanisms of non-alcoholic steatohepatitis and exploring potential therapeutic approaches.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRapirosiran is an N-acetylgalactosamine-conjugated small interfering RNA that specifically targets mRNA of hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) in the liver. Inhibition of HSD17B13 via Rapirosiran is associated with a reduced risk of chronic liver disease. This reagent is valuable for investigating the mechanisms of non-alcoholic steatohepatitis and exploring potential therapeutic approaches.
Product Information
Catalog NumA68985
Molecular Weight16307.22
CAS Number2755196-97-3
SMILES[Rapirosiran]
SynonymsALN-HSD; ALN-288996; AD-288996
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