Fig. 1 · Structure
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Raseglurant hydrochloride
mGluR5 NAM
Raseglurant hydrochloride is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5). This compound is primarily utilized in research exploring its effects on neurological conditions, particularly migraines, by modulating glutamatergic signaling pathways. Its role in targeting mGluR5 offers potential insights into therapeutic strategies for related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 757949-98-7 |
| Applications | mGluR5 NAM |
| Formula | C15H14ClFN2 |
| Molecular Weight | 276.74 |
| Synonyms | ADX-10059 hydrochloride |
| SMILES | NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.