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RBx-7796 sodium

5-LO Inhibitor

RBx-7796 sodium is a competitive and highly selective inhibitor of 5-lipoxygenase (5-LO), exhibiting an IC50 value of 3.5 mM for the human enzyme. This compound effectively suppresses 5-LO activity and the subsequent release of leukotriene B4 (LTB4), making it a valuable tool for research into airway inflammation. Its ability to significantly reduce bronchial constriction positions RBx-7796 sodium as a potential therapeutic candidate in the study of respiratory disorders associated with inflammatory responses.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	794528-96-4
Applications	5-LO Inhibitor
Formula	C₃₀H₄₇N₂NaO₇
Molecular Weight	570.69
SMILES	O=C(O[Na])CC(C=C1)=CC=C1NC(N[C@H]([C@]2([H])[C@@]3([H])[C@@](OC(C)(C)O3)([H])[C@@H](OCCCCCCCCCCCC)O2)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.