Fig. 1 · Structure
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RC-33 hydrochloride
Apoptosi Inducer
RC-33 hydrochloride is a selective and metabolically stable sigma receptor agonist that induces apoptosis and enhances nerve growth factor (NGF)-induced neurite outgrowth. Both enantiomers exhibit similar affinity for the sigma receptor, demonstrating comparable effectiveness in modulating receptor activity. Notably, the R-enantiomer exhibits greater metabolic stability in liver environments when exposed to NADPH. This profile positions RC-33 hydrochloride as a promising candidate for in vivo studies, particularly in animal models of amyotrophic lateral sclerosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1346016-43-0 |
| Applications | Apoptosi Inducer |
| Formula | C21H28ClN |
| Molecular Weight | 329.91 |
| SMILES | CC(C1=CC=C(C2=CC=CC=C2)C=C1)CCN3CCCCC3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.