Fig. 1 · Structure

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Rebimastat

MMP Inhibitor

Rebimastat is an orally active, broad-spectrum inhibitor of matrix metalloproteinases (MMPs) and a non-peptide collagen mimetic. It exhibits selective inhibition, allowing for modulation of specific MMP activities without affecting all collagenase functions. Rebimastat is utilized in research related to colorectal cancer, providing insights into the role of MMPs in tumor progression and metastasis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 259188-38-0
Applications MMP Inhibitor
Formula C23H41N5O5S
Molecular Weight 499.67
Synonyms BMS 275291
SMILES
CNC([C@H](C(C)(C)C)NC([C@H](CC(C)C)NC([C@@H](S)CCN1C(C(C)(N(C1=O)C)C)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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