rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride

Catalog No.: A25511
Stable Isotope
rel-(1S,2R)-Dihydro bupropion-d9 hydrochloride is a deuterated form of rel-(1S,2R)-Dihydro bupropion hydrochloride, a metabolite of the widely known antidepressant bupropion. This compound is a stable isotope that facilitates studies on cytokine modulation, specifically promoting endogenous IL-10 production while inhibiting Th1 cytokines such as IL-12 and TNF-α. Additionally, rel-(1S,2R)-Dihydro bupropion influences immune response dynamics, shifting from a Th1 to Th2 response. It is valuable for research focused on inflammatory conditions and immunological response pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionrel-(1S,2R)-Dihydro bupropion-d9 hydrochloride is a deuterated form of rel-(1S,2R)-Dihydro bupropion hydrochloride, a metabolite of the widely known antidepressant bupropion. This compound is a stable isotope that facilitates studies on cytokine modulation, specifically promoting endogenous IL-10 production while inhibiting Th1 cytokines such as IL-12 and TNF-α. Additionally, rel-(1S,2R)-Dihydro bupropion influences immune response dynamics, shifting from a Th1 to Th2 response. It is valuable for research focused on inflammatory conditions and immunological response pathways.
Product Information
Catalog NumA25511
FormulaC13H12D9Cl2NO
Molecular Weight287.27
CAS Number2517771-79-6
SMILES[2H]C(C(C([2H])([2H])[2H])(N[C@@H]([C@H](C1=CC(Cl)=CC=C1)O)C)C([2H])([2H])[2H])([2H])[2H].Cl
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