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rel-Biotin-PEG3-C3-NH2

PROTAC Linker

rel-Biotin-PEG3-C3-NH2 is a PEG-based linker specifically designed for the construction of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the selective degradation of target proteins by promoting the engagement of E3 ubiquitin ligases. Its biological activity is essential for advancing research in protein homeostasis and therapeutic applications targeting disease-related proteins.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1374658-86-2
Applications	PROTAC Linker
Formula	C₂₀H₃₈N₄O₅S
Molecular Weight	446.61
SMILES	O=C(NCCCOCCOCCOCCCN)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.