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Biological Activity
Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM, respectively. Antiviral agent.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.21 mL | 156.05 mL | 312.1 mL |
| 0.5 mM | 6.24 mL | 31.21 mL | 62.42 mL |
| 1 mM | 3.12 mL | 15.61 mL | 31.21 mL |
| 5 mM | 0.62 mL | 3.12 mL | 6.24 mL |
*The above data is based on the productmolecular weight 320.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A19048 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1429192-00-6 |
| Formula | C19H16N2OS |
| M. Wt | 320.41 |
| Purity | >98% |
| Synonyms | RN 1-001, RN1-001, RN-1-001 |
| SMILES | O=C1C2=CC=CC=C2NC(N1C3=CC=CC=C3)C4=CC=C(S4)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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