RFB4 is an anti-CD22 monoclonal antibody that specifically targets the CD22 antigen, a marker commonly expressed on B-cell malignancies. This antibody can be utilized to generate recombinant immunotoxins by fusing with the pseudomonas exotoxin PE38 through disulfide linkages, such as in the construct RFB4(dsFv)-PE38. RFB4 serves as a vital tool for research focused on cancer, particularly in studies related to lymphoma and other B-cell related diseases.
RFB4 is an anti-CD22 monoclonal antibody that specifically targets the CD22 antigen, a marker commonly expressed on B-cell malignancies. This antibody can be utilized to generate recombinant immunotoxins by fusing with the pseudomonas exotoxin PE38 through disulfide linkages, such as in the construct RFB4(dsFv)-PE38. RFB4 serves as a vital tool for research focused on cancer, particularly in studies related to lymphoma and other B-cell related diseases.
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