Total item
Cart Subtotal
$0.00 Details
RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.74 mL | 68.7 mL | 137.4 mL |
| 0.5 mM | 2.75 mL | 13.74 mL | 27.48 mL |
| 1 mM | 1.37 mL | 6.87 mL | 13.74 mL |
| 5 mM | 0.27 mL | 1.37 mL | 2.75 mL |
*The above data is based on the productmolecular weight 727.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A11523 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 727.78 |
| Formula | C38H48Cl2N4O4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 939981-39-2 |
| Synonyms | RG-7112, RG 7112, RO5045337 |
| SMILES | CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
NSC-207895 (XI-006)
NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A…
Idasanutlin (RG7388)
Idasanutlin is a potent and selective p53-MDM2 inhibitor.
Pifithrin-u
inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL.
PhiKan 083
PhiKan 083, p53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protei…
Nutlin 3a
Nutlin 3a is a potent inhibitor of MDM2 (mouse double minute 2) binding to p53 that induces the expression of p53 regulated genes, and shows…
Pifithrin-alpha
Pifithrin-a is a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription such as cyclin G, p21/waf1, and mdm2 ex…
MIRA-1
MIRA-1 restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21,…
Keywords:buy RG7112 | RG7112 Supplier | purchase RG7112 | RG7112 cost | RG7112 manufacturer | order RG7112 | RG7112 distributor | buy 939981-39-2| 939981-39-2 Supplier | purchase 939981-39-2 | 939981-39-2 cost | 939981-39-2 manufacturer | order 939981-39-2 | 939981-39-2 distributor
Adooq Quality Guarantee
We promise all products perform as described.