Rho GTPase Inhibitor 1 is a selective inhibitor targeting Rho GTPases, with demonstrated high affinity for Cdc42, Rac1, and RhoA, exhibiting KDs of 151, 352, and 232 μM, respectively. This compound effectively reduces cell migration in glioma cell lines, highlighting its potential utility in cancer research and therapeutic development. Its role in modulating Rho GTPase signaling makes it a valuable tool for investigating cellular processes such as motility and invasion.
Rho GTPase Inhibitor 1 is a selective inhibitor targeting Rho GTPases, with demonstrated high affinity for Cdc42, Rac1, and RhoA, exhibiting KDs of 151, 352, and 232 μM, respectively. This compound effectively reduces cell migration in glioma cell lines, highlighting its potential utility in cancer research and therapeutic development. Its role in modulating Rho GTPase signaling makes it a valuable tool for investigating cellular processes such as motility and invasion.
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