Rigosertib

Catalog No.: A21868

multi-kinase inhibitor

Rigosertib

Rigosertib Chemical Structure

CAS NO. 592542-59-1

Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle.

Availability: In stock

Package Price Qty
5 mg
$76.00
10 mg
$130.00
50 mg
$386.00
100 mg
$773.00
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Biological Activity

Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.15 mL 110.74 mL 221.49 mL
0.5 mM 4.43 mL 22.15 mL 44.3 mL
1 mM 2.21 mL 11.07 mL 22.15 mL
5 mM 0.44 mL 2.21 mL 4.43 mL

*The above data is based on the productmolecular weight 451.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21868
Actions Inhibitor
M. Wt 451.49
Formula C21H25NO8S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 592542-59-1
Synonyms ON-01910, ON01910, ON 01910
SMILES COC1=CC=C(C=C1NCC(O)=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O.[(E)]

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