Fig. 1 · Structure
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Rivastigmine carbamate impurity
ChE Inhibitor
Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is a byproduct of Rivastigmine, a potent cholinesterase (ChE) inhibitor. This compound selectively inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), demonstrating IC50 values of 0.037 μM and 4.15 μM, respectively. Rivastigmine carbamate impurity is primarily utilized in the investigation of cholinergic system modulation and the pharmacological profiling of cholinesterase inhibitors in neurodegenerative disease research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1346242-31-6 |
| Applications | ChE Inhibitor |
| Formula | C10H12N2O4 |
| Molecular Weight | 224.21 |
| Synonyms | 3-Nitrophenyl ethyl(methyl)carbamate |
| SMILES | O=C(OC1=CC=CC([N+]([O-])=O)=C1)N(CC)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.