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RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.86 mL | 114.32 mL | 228.64 mL |
| 0.5 mM | 4.57 mL | 22.86 mL | 45.73 mL |
| 1 mM | 2.29 mL | 11.43 mL | 22.86 mL |
| 5 mM | 0.46 mL | 2.29 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18893 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 437.36 |
| Formula | C21H26Cl2N4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2172651-73-7 |
| Synonyms | RMC4550, RMC-4550 |
| SMILES | ClC1=C(Cl)C(C2=NC(CO)=C(N3CCC4(CO[[email protected]@H](C)[[email protected]]4N)CC3)N=C2C)=CC=C1 |
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