RMC-4550

Catalog No.: A18893

SHP2 inhibitor

RMC-4550

RMC-4550 Chemical Structure

CAS NO. 2172651-73-7

RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM.

Availability: In stock

Package Price Qty
1 mg
$150.00
5 mg
$420.00
10 mg
$600.00
50 mg
$1,800.00
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Biological Activity

RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM.
In vitro DMSO 91 mg/mL (208.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.86 mL 114.32 mL 228.64 mL
0.5 mM 4.57 mL 22.86 mL 45.73 mL
1 mM 2.29 mL 11.43 mL 22.86 mL
5 mM 0.46 mL 2.29 mL 4.57 mL

*The above data is based on the productmolecular weight 437.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18893
Actions Inhibitor
CAS No. 2172651-73-7
Formula C21H26Cl2N4O2
M. Wt 437.36
Purity >98%
Synonyms RMC4550, RMC-4550
SMILES ClC1=C(Cl)C(C2=NC(CO)=C(N3CCC4(CO[[email protected]@H](C)[[email protected]]4N)CC3)N=C2C)=CC=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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