RN-1734

Catalog No.: A20616
TRPV4 antagonist
RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM).
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Product Name Price Stock Qty
RN-1734 5mg
$54.00
In stock
RN-1734 10mg
$93.00
In stock
RN-1734 50mg
$276.00
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RN-1734 100mg
$552.00
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Biological Activity
Discription RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM).
Product Information
Catalog Num A20616
Formula C14H22Cl2N2O2S
Molecular Weight 353.31
CAS Number 946387-07-1
SMILES O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O
Synonyms RN1734, RN 1734
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 63 mg/mL (178.31 mM)
Water Insoluble
Ethanol 63 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.3 mL 141.52 mL 283.04 mL
0.5 mM 5.66 mL 28.3 mL 56.61 mL
1 mM 2.83 mL 14.15 mL 28.3 mL
5 mM 0.57 mL 2.83 mL 5.66 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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