RN-9893

Catalog No.: A68740
TRPV4 Receptor Antagonist
RN-9893 is a potent and selective antagonist of the TRPV4 receptor, exhibiting IC50 values of 320 nM, 420 nM, and 660 nM for mouse, human, and rat channels, respectively. This compound is valuable for research applications involving the modulation of TRPV4-mediated physiological processes. Its selective inhibition can aid in studies related to pain sensation, inflammation, and other TRPV4-associated diseases.
Grouped product items
Size Price Stock Qty
1mg
$30.00
In stock
5mg
$75.00
In stock
10mg
$125.00
In stock
25mg
$190.00
In stock
50mg
$280.00
In stock
100mg
$400.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRN-9893 is a potent and selective antagonist of the TRPV4 receptor, exhibiting IC50 values of 320 nM, 420 nM, and 660 nM for mouse, human, and rat channels, respectively. This compound is valuable for research applications involving the modulation of TRPV4-mediated physiological processes. Its selective inhibition can aid in studies related to pain sensation, inflammation, and other TRPV4-associated diseases.
Product Information
Catalog NumA68740
FormulaC21H23F3N4O5S
Molecular Weight500.49
CAS Number1803003-68-0
SMILESO=S(C(C=C1)=CC=C1NC(C2=C([N+]([O-])=O)C=C(C(F)(F)F)C=C2)=O)(N3CCN(C(C)C)CC3)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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