RNF5 agonist 1

Catalog No.: A42480
RNF5 Agonist
RNF5 Agonist 1 is a potent activator of RNF5, enhancing its biological function. This compound significantly increases the ubiquitylation of ATG4B in F508del-CFTR-expressing CFBE41o- cells, indicating its potential utility in studies of protein degradation pathways and cystic fibrosis research. RNF5 Agonist 1 serves as a valuable tool for investigating the role of RNF5 in cellular processes and therapeutic interventions.
Grouped product items
Size Price Stock Qty
5mg
$305.00
In stock
10mg
$475.00
In stock
25mg
$950.00
In stock
50mg
$1,395.00
In stock
100mg
$2,050.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRNF5 Agonist 1 is a potent activator of RNF5, enhancing its biological function. This compound significantly increases the ubiquitylation of ATG4B in F508del-CFTR-expressing CFBE41o- cells, indicating its potential utility in studies of protein degradation pathways and cystic fibrosis research. RNF5 Agonist 1 serves as a valuable tool for investigating the role of RNF5 in cellular processes and therapeutic interventions.
Product Information
Catalog NumA42480
FormulaC22H18N4S
Molecular Weight370.47
CAS Number69909-92-8
SMILESCC1=NS/C(N1C2=CC=CC=C2)=N\C(C3=CC=CC=C3)=N\C4=CC=CC=C4
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