Fig. 1 · Structure

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Ro 20-0083

Human Pancreatic Lipase Inhibitor

Ro 20-0083 is a selective inhibitor of human pancreatic lipase, prominently engaged in diminishing lipid absorption and regulating de novo fatty acid synthesis. This compound exhibits significant effects on reducing food intake, as demonstrated in studies with Zucker rats. Ro 20-0083 is a valuable tool for research related to obesity and metabolic disorders, facilitating investigations into fat metabolism and energy balance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 31478-25-8
Applications Human Pancreatic Lipase Inhibitor
Formula C33H51N2NaO10
Molecular Weight 658.76
SMILES
CC[C@]1([C@]2([H])O[C@H]([C@@](CC2)(O[Na])CC)C)O[C@]([C@H](C1)C)([H])[C@@H](CC)C([C@@H](C)[C@@H](O)[C@H](C)CCC3=C(C(O)=C(C=C3[N+]([O-])=O)C)[N+]([O-])=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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