Fig. 1 · Structure
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Ro24-7429
Tat Antagonist
Ro24-7429 is a potent antagonist of the HIV-1 transactivator protein Tat, functioning primarily to inhibit Tat-mediated transcriptional activation. Additionally, Ro24-7429 acts as a runt-related transcription factor 1 (RUNX1) inhibitor. This compound exhibits significant biological activities, including anti-HIV, antifibrotic, and anti-inflammatory effects, making it a valuable tool for research applications in virology, fibrosis, and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 139339-45-0 |
| Applications | Tat Antagonist |
| Formula | C14H13ClN4 |
| Molecular Weight | 272.73 |
| SMILES | CNC1=NC2=CC=C(Cl)C=C2C(C3=CC=CN3)=NC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.