Fig. 1 · Structure
Documents & Downloads
RO3244794
Prostacyclin Receptor Antagonist
RO3244794 is a potent and selective antagonist of the prostacyclin receptor (IP receptor), demonstrating a pKi value of 7.7 in human platelets and 6.9 in a recombinant IP receptor system. This compound shows significant analgesic and anti-inflammatory properties, making it a valuable tool for researchers investigating pain mechanisms and inflammatory conditions. Its specificity and efficacy contribute to its potential applications in pharmacological studies related to cardiovascular diseases and other related disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 361457-01-4 |
| Applications | Prostacyclin Receptor Antagonist |
| Formula | C25H19F2NO5 |
| Molecular Weight | 451.42 |
| SMILES | FC(C=C1)=CC=C1C[C@H](C(O)=O)NC(OCC2=CC3=CC(C4=CC=C(C=C4)F)=CC=C3O2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.