Rocaglamide

Catalog No.: A12765

HSF1 activation inhibitor

Rocaglamide

Rocaglamide Chemical Structure

CAS NO. 84573-16-0

Rocaglamide (Rocaglamide A) is isolated from the genus Aglaia and can be used to treat coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.

Availability: In stock

Package Price Qty
1 mg
$180.00
5 mg
$620.00
10 mg
$980.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Rocaglamide (Rocaglamide A) is isolated from the genus Aglaia and can be used to treat coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.78 mL 98.9 mL 197.8 mL
0.5 mM 3.96 mL 19.78 mL 39.56 mL
1 mM 1.98 mL 9.89 mL 19.78 mL
5 mM 0.4 mL 1.98 mL 3.96 mL

*The above data is based on the productmolecular weight 505.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12765
Actions Inhibitor
CAS No. 84573-16-0
Formula C29H31NO7
M. Wt 505.56
Purity >98%
Synonyms Rocaglamide A, RocA, NSC 326408
SMILES O=C([[email protected]]([[email protected]]1C2=CC=CC=C2)[[email protected]@H](O)[[email protected]]3(O)[[email protected]@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)N(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Rocaglamide | Rocaglamide Supplier | purchase | cost | manufacturer | order | distributor | buy 84573-16-0| 84573-16-0 Supplier | purchase 84573-16-0 | 84573-16-0 cost | 84573-16-0 manufacturer | order 84573-16-0 | 84573-16-0 distributor
Rewards