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Rolapitant Intermediate

Catalog No.: A98150
Drug Intermediate
Rolapitant Intermediate, chemically defined as (3R,7aR)-3-(tert-Butyl)-1-hydroxy-7a-vinyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-one, serves as a critical drug intermediate in the synthesis of diverse active pharmaceutical ingredients. This intermediate is essential in the development of compounds with potential applications in the prevention and management of nausea and vomiting in patients undergoing chemotherapy. Its role in medicinal chemistry facilitates the creation of innovative therapeutics targeting related conditions.
Rolapitant Intermediate 1214741-21-5 Drug Intermediate
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Size Price Stock Qty
100mg
$30.00
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250mg
$60.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRolapitant Intermediate, chemically defined as (3R,7aR)-3-(tert-Butyl)-1-hydroxy-7a-vinyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-one, serves as a critical drug intermediate in the synthesis of diverse active pharmaceutical ingredients. This intermediate is essential in the development of compounds with potential applications in the prevention and management of nausea and vomiting in patients undergoing chemotherapy. Its role in medicinal chemistry facilitates the creation of innovative therapeutics targeting related conditions.
Product Information
Catalog NumA98150
FormulaC12H19NO3
Molecular Weight225.28
CAS Number1214741-21-5
SMILESCC(C)(C)[C@H]1OC(O)[C@@]2(CCC(=O)N12)C=C
Synonyms(3R,7aR)-3-(tert-Butyl)-1-hydroxy-7a-vinyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-one
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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