Fig. 1 · Structure
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RORγ agonist 1
Cat. No.
A77580
CAS
2260631-91-0
ROR Agonist
RORγ Agonist 1 is a potent agonist of the RORγ nuclear receptor, exhibiting an EC50 of 21 nM. This compound demonstrates significant antitumor activity, making it a valuable tool in cancer research. Its oral bioavailability facilitates convenient administration in preclinical studies exploring RORγ's role in tumor progression and immune modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2260631-91-0 |
| Applications | ROR Agonist |
| Formula | C29H27ClF4N2O4S |
| Molecular Weight | 611.05 |
| SMILES | FCCN1C2=CC=C(C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CO)=O)C=C2C=C1CC4=C(C=C(C=C4)Cl)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.