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RORγ-IN-2

Name: RORγ-IN-2
Brand: Adooq Bioscience
SKU: A77608
Availability: OutOfStock

Cat. No. A77608 CAS 2088333-58-6

RORγ Inhibitor

RORγ-IN-2 is a selective inhibitor of RAR-related orphan receptor gamma (RORγ) with a Ki of 16.6 nM for human RORγ. This compound is primarily utilized in research focused on IL-17-dependent autoimmune diseases, providing insights into the modulation of immune responses and inflammation. RORγ-IN-2 serves as a valuable tool for investigating the therapeutic potential of targeting RORγ in various pathological conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2088333-58-6
Applications	RORγ Inhibitor
Formula	C₂₈H₃₂F₃N₅O₄S₂
Molecular Weight	623.71
SMILES	CCS(C(C=N1)=CC=C1CNC(C2=CC3=C(C4(O[C@H](C3)C)CCN(CC4)[C@@H](C5=CN=C(C(F)(F)F)N=C5)C)S2)=O)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.