Fig. 1 · Structure

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RORγ inverse agonist 1

Cat. No. A77561 CAS 529500-72-9

RORγ Inverse Agonist

RORγ inverse agonist 1 is an inverse agonist of the retinoic acid receptor-related orphan receptor gamma (RORγ). This compound modulates RORγ activity, negatively regulating its transcriptional activity. It is primarily utilized in research related to immune responses and inflammation, offering insights into potential therapeutic strategies targeting autoimmune diseases and related disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inverse Agonist
CAS Number 529500-72-9
Applications RORγ Inverse Agonist
Formula C22H20F3N3O3S
Molecular Weight 463.47
SMILES
O=C(NCC1=CC=NC=C1)CN(S(=O)(C2=CC=C(C)C=C2)=O)C3=CC=CC(C(F)(F)F)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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