Fig. 1 · Structure

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RORγ inverse agonist 2

Cat. No. A77596 CAS 1242610-59-8

RORγ Inverse Agonist

RORγ inverse agonist 2 is a potent inverse agonist targeting the retinoic acid receptor-related orphan receptor RORγ, exhibiting IC50 values of 0.4 μM and 0.9 μM for Gal4-RORγ and full-length RORγ, respectively. This compound is significant for research applications focused on autoimmune diseases, providing insights into RORγ's role in immune regulation and pathology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inverse Agonist
CAS Number 1242610-59-8
Applications RORγ Inverse Agonist
Formula C35H48O4
Molecular Weight 532.75
SMILES
CC1(C)C(/C(C[C@]2(C)[C@@]3([H])CC[C@]4([H])[C@@]5([H])[C@H](C(C)=C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=C\C6=CC=CO6)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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