Fig. 1 · Structure
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RORγt agonist 2
Cat. No.
A77592
CAS
2663787-92-4
RORγt Agonist
RORγt Agonist 2 is a selective agonist of the Retinoic acid receptor-related orphan receptor gamma t (RORγt), which plays a critical role in the differentiation of Th17 cells. This compound enhances the production of pro-inflammatory cytokines, thereby increasing lymphocyte cytotoxicity. Additionally, RORγt Agonist 2 inhibits the generation of regulatory T cells, ultimately promoting a more robust immune response. Its applications include research in autoimmune diseases and immunotherapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2663787-92-4 |
| Applications | RORγt Agonist |
| Formula | C30H30F3N3O4S |
| Molecular Weight | 585.64 |
| SMILES | CC(C1N(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C(N[C@H](C4=CC=C(C=C4)S(CC)(=O)=O)CC#N)=O)C=C3OC1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.