Fig. 1 · Structure
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RORγt inhibitor 2
Cat. No.
A77604
CAS
2673278-10-7
RORγt Inhibitor
RORγt Inhibitor 2 is a selective inhibitor of the RORγt transcription factor, exhibiting an IC50 value of 9.2 nM. This compound demonstrates significant anti-inflammatory and immunomodulatory activity, making it a valuable tool for research into cancer, autoimmune disorders, and inflammatory conditions driven by RORγt signaling. Its specificity and potency enable detailed studies of RORγt's biological roles and therapeutic potential.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2673278-10-7 |
| Applications | RORγt Inhibitor |
| Formula | C31H33F5N2O7S |
| Molecular Weight | 672.66 |
| SMILES | FC(F)OC[C@H]1N(C2=CC=C(C=C2)C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CCO)=O)C[C@H](C1)OC4=CC=C(C=C4)OC(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.